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Updated: Sep 18, 2025

Measuring Cation Transport by Na,K- and H,K-ATPase in Xenopus Oocytes by Atomic Absorption Spectrophotometry: An Alternative to Radioisotope Assays
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开发Na,K-ATPase-α4抑制剂作为男性避孕药的策略

Shameem S Syeda1, Gladis Sánchez2, Jeffrey P McDermott2

  • 1Department of Medicinal Chemistry, Institute for Therapeutics Discovery and Development, College of Pharmacy, University of Minnesota, Minneapolis, MN 55414, USA.

International journal of molecular sciences
|June 26, 2025
PubMed
概括

开发新的男性避孕药非常重要. 研究人员简化了复杂的分子,以创建新的NKAα4抑制剂,其中化合物45通过减少精子运动和阻止受精,显示出对非荷尔蒙男性避孕的希望.

关键词:
和简化的小分子.男人的避孕药是男人的避孕药.男人的生育能力 男人的生育能力乌阿巴林,就是这样.简化的类固醇类似物.精子容量化能力 精子容量化能力精子运动性 精子运动性

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