狄克洛芬雅克免疫媒介性肝炎:鉴定临床相关剂量的先天性和适应性免疫反应

Jürgen Borlak1, Reinhard Spanel1

  • 1Hannover Medical School, Centre for Pharmacology and Toxicology, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.

概括

在迷你猪中,迪克洛菲纳克治疗诱导了显著的先天性和适应性免疫反应,导致肝脏炎症和损伤. 这项研究揭示了参与迪克洛芬雅克诱导的肝炎的关键免疫路径.

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