深度学习应用程序的综合性审查与多omics数据在癌症研究中的数据
Flavio Sartori1, Francesco Codicè1, Isabella Caranzano1
1Computational Biomedicine Unit, Department of Medical Sciences, University of Torino, Via Santena 19, 10126 Torino, Italy.
Genes
|June 26, 2025
概括
与多omics数据集成的深度学习模型通过识别生物标志物和改善患者治疗来彻底改变癌症研究. 本综述涵盖了癌症基因组学,分类和药物反应预测的深度学习的最新进展.
科学领域:
- 生物信息学是一种生物信息学.
- 计算生物学 计算生物学
- 基因组学就是基因组学.
背景情况:
- 深度学习 (DL) 和多学科数据集成正在改变生物系统分析,特别是在癌症研究中.
- DL促进了高维数据分析,揭示了新的疾病机制和生物标志物,以改善患者护理.
研究的目的:
- 为癌症基因组学应用的最新深度学习模型提供全面的审查.
- 专注于包括癌症类型分类,驱动基因识别,生存分析和药物反应预测在内的关键应用.
主要方法:
- 自2020年以来出版的方法的系统审查.
- 分析深度学习模型架构,数据集和创新.
- 解释基本的机器学习和深度学习概念以及多omics数据特征.
主要成果:
- 最近的深度学习模型显示了癌症基因组学应用的巨大潜力.
- 突出了模型架构和数据集成中的关键创新.
- 该审查涵盖了分类,驱动基因识别,生存分析和药物反应预测方面的进展.
结论:
- 深度学习与多omics数据的整合为推进癌症研究提供了强大的工具.
- 这些进展对于开发改进的诊断和治疗策略至关重要.
- 该评论服务于对癌症生物学计算方法感兴趣的跨学科观众.
更多相关视频
08:51Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts
Published on: September 20, 2024
1.5K
07:47Author Spotlight: Unveiling Transmembrane Protein Family-Related Markers in Gastric Cancer and Implications for Targeted Therapies
Published on: September 15, 2023
1.7K
相关概念视频
02:02Genomics
37.5K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
37.5K
02:43Mouse Models of Cancer Study
5.7K
Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
5.7K