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驴皮凝酸铁复合物:结构特征,在模拟消化下增强铁的溶解性,以及双重铁化-抗氧化功能

Lili Yang^1,2, Chenyan Lv², Xingfeng Guo¹

¹Shandong Key Laboratory of Applied Technology for Protein and Peptide Drugs, School of Pharmaceutical Sciences and Food Engineering, Liaocheng University, Liaocheng 252059, China.

Foods (Basel, Switzerland)

|June 26, 2025

概括

新型驴皮凝呈现出作为铁补充剂的前景. 这些低分子量驴皮凝 (LMW DHGP) 有效合铁,改善吸收和抗氧化活性,用于潜在的食品应用.

科学领域:

营养生物化学营养生物化学
食品科学食品科学食品科学
生物技术是生物技术.

背景情况:

缺铁是一个重要的全球健康问题.
开发具有增强吸收的有效铁补充剂至关重要.
铁补充剂的新来源正在积极研究中.

研究的目的:

调查低分子量驴皮凝 (LMW DHGP) 作为一种新型铁补充剂的潜力.
描述LMW DHGP-铁复合物的铁化特性和结构特征.
评估这些复合物的体外消化稳定性和抗氧化活性.

主要方法:

驴皮凝的酶化水解产生LMW DHGP.
铁化能力测试. 铁化能力测试.
扫描电子显微镜 (SEM),X射线衍射 (XRD),循环二元化 (CD) 和富里埃变换红外光谱 (FTIR) 用于结构分析.
在体外消化稳定性研究.
抗氧化剂活性测定 (DPPH和ABTS).

主要成果:

LMW DHGP 显示出高铁合能力 (249.98 μg/mg),可能涉及关键氨基酸如 Asn,Gly,Cys 和 Lys.
SEM和XRD揭示了LMWDHGP铁复合物的粗,多孔无形结构.
磁盘光谱显示了由体α-螺旋结构介导的自我组装,而FTIR证实了通过炭基和氨基基群的相互作用.
与硫酸铁 (FeSO4) 相比,LMW DHGP-铁复合物在体外消化过程中显示出优越的铁离子溶解性.
PGPAG-铁复合体表现出显著的抗氧化活性,具有较高的DPPH和ABTS基的清除率.

结论:

LMW DHGP-铁复合体表现出优异的铁结合和溶解性质,这表明其生物可用性得到了提高.
LMW DHGP 的结构特征和功能组促进了有效的铁化.
这些复合物具有显著的抗氧化能力,增加了它们潜在的健康益处.
LMW DHGP-铁复合物代表了铁强化食品和补充剂的有前途的新成分.

关键词:

抗氧化剂活性抗氧化剂活性驴皮的凝酸是一种凝.酸铁结合物 - 铁结合物分析光谱学分析.结构性特征的结构性特征.

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