低剂量内甘他素注射用于吸收性阴道病:有多少是最佳的?
Joon-Pyo Hong1,2, Hayoung Byun1, Min-Beom Kim1,3
1Department of Otorhinolaryngology-Head and Neck Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul 03181, Republic of Korea.
Journal of clinical medicine
|June 26, 2025
概括
对于难以治愈的Meniere来说.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 神经学 神经学
背景情况:
- 梅尼尔氏病 (MD) 在治疗难治性的管理中提出了挑战.
- 低剂量内膜内素注射 (ITGM) 是MD的一种治疗选择.
研究的目的:
- 为了比较单次与多次低剂量ITGM治疗难治的MD的结果.
- 确定ITGM重复的最佳数量,以控制和保护听力.
主要方法:
- 对33名确定的MD患者接受低剂量ITGM治疗的回顾性审查 (2015-2020年).
- 患者分为单次注射 (n=14) 和多次注射 (n=19) 组.
- 在ITGM重复时评估的听力测量,热量测试和视频头部脉冲测试 (vHIT).
主要成果:
- 第一次ITGM在两组没有听力损失的情况下降低了热量反应和vHIT增长.
- 第二次ITGM改善了8/19名患者的头和前庭功能.
- 第三个和第四个ITGM没有显示任何额外的益处,在多次注射组中观察到听力恶化.
结论:
- 最多两次低剂量ITGM手术可能对复发性或反应不良的MD有益.
- 考虑在两次ITGM后进行替代疗法,如果头持续存在,以保持听力.
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