在急诊室的早期尿液输出是进行连续脏置换的重症患者的预后指标
Soo Hyun Han1, Changshin Kang2, Hyerim Park3
1Department of Nephrology, College of Medicine, Chungnam National University, 266 Munwha-ro, Jung-gu, Daejeon 35015, Republic of Korea.
Life (Basel, Switzerland)
|June 26, 2025
概括
在急诊室的初始低尿量预测,在接受连续脏替代疗法 (CRRT) 的重症患者中,死亡率更高. 高尿量与更好的生存和脏恢复有关.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 关键护理医学 关键护理医学
- 脏替代疗法治疗 脏替代疗法
背景情况:
- 持续置换疗法 (CRRT) 对患有损伤的重症患者至关重要.
- 对于CRRT患者的预测结果,特别是来自急诊室 (ER) 评估的早期指标,需要进一步澄清.
研究的目的:
- 确定初始急诊室 (ER) 因素是否会影响接受CRRT的重症患者的存活率和功能.
- 确定该患者群体中死亡率和恢复的早期预测因素.
主要方法:
- 对190名接受CRRT的重症患者的回顾性分析,通过ER启动.
- 临床参数的评估,包括6小时尿液输出,估计的淋巴细胞过率 (eGFR) 和中性粒细胞凝酶相关的脂卡林 (NGAL).
- 主要结局:30天和90天死亡率;次要结局:没有RRT的持续时间.
主要成果:
- 在最初的6小时内尿量低 (LUO) 与30天和90天死亡率的增加显著相关 (HRs1.935和2.141).
- 在死亡率和初始EGFR或血NGAL水平之间没有发现显著的关联.
- 高尿量 (HUO) 和初始eGFR≥30mL/min/1.73m2与30天和90天更长的无RRT持续时间相关.
结论:
- 在急诊室最初6小时的尿液输出是接受CRRT的重症患者30天和90天死亡率的重要预测因素.
- 在ER的早期尿量评估可以帮助CRRT患者的风险分层.
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