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轮班工作,社会人口统计学和生活方式特征,身体测量和MASLD之间的关联

Javier Tosoratto¹, Pedro Juan Tárraga López^2,3, Ángel Arturo López-González^1,4,5,6

¹Investigation Group ADEMA SALUD, University Institute for Research in Health Sciences (IUNICS), 07010 Palma, Balearic Islands, Spain.

Life (Basel, Switzerland)

|June 26, 2025

概括

轮班工作显著增加了与代谢功能障碍相关的脂肪性肝病 (MASLD) 的风险,特别是在女性和蓝领工人中. 建议在职业计划中进行肝脏健康查.

科学领域:

职业健康职业健康职业健康
肝病学肝病学是一种肝病学.
代谢障碍代谢障碍代谢障碍

背景情况:

与代谢功能障碍相关的脂肪性肝病 (MASLD) 是与代谢综合征相关的全球健康问题.
轮班工作扰乱昼夜节律,可能导致代谢功能障碍和肝脏疾病.
关于轮班工作与大量,多样化的劳动力中MASLD的关联存在有限的数据.

研究的目的:

调查轮班工作与西班牙工人的MASLD风险之间的关联.
用多个非侵入性指数评估MASLD风险.
探索社会人口统计学,生活方式和性对这种协会的影响.

主要方法:

在53,053名西班牙工人 (2019-2020年) 的横截面研究中.
使用七个经过验证的非侵入性指数 (FLI,HSI,ZJU,FLD,FSI,LAP,BARD) 评估了MASLD风险.
多项逻辑回归分析了轮班工作和MASLD风险之间的关联,控制了混因素.

主要成果:

与非轮班工人相比,轮班工人在所有指数中显示出更高的MASLD风险得分.
轮班工作独立地与增加的MASLD风险相关 (例如,HSI OR:7.83,ZJU OR:5.91).
男性性别,年龄较大,吸烟和蓝领地位也与较高的MASLD风险有关.

结论:

轮班工作是MASLD的一个重要,独立的风险因素.
女性和蓝领工人可能特别容易受到轮班工作对肝脏的影响.
职业健康计划应包括MASLD查和有针对性的干预措施.

关键词:

马斯尔德马斯尔德是什么意思生活方式习惯习惯肝脏指数肝脏指数代谢健康的代谢健康轮班工作是轮班工作.社会人口学因素社会人口学因素

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