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Updated: Sep 18, 2025

Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter
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针对NEDD4L-eEF1A1轴在癌症治疗中的治疗潜力

Yan Qin1,2,3,4, Xinyue Wang2, Minghui Zhao4,5

  • 1Central Laboratory, Affiliated Hospital of Hebei University, Baoding 071000, China.

Acta biochimica et biophysica Sinica
|June 26, 2025
PubMed
概括

神经元前体细胞表达发育下调4样 (NEDD4L) 通过降解内皮细胞中的eEF1A1来抑制瘤血管生成. 损失NEDD4L促进瘤生长和血管生成,突出显示NEDD4L-eEF1A1轴作为治疗点.

关键词:
在NEDD4L中,它是NEDD4L.血管新生是因为血管新生.自自是自的过程.eEF1A1A1 的使用情况.移民 移民 迁移 迁移它们的扩散和扩散.无处不在的化

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