分支视网膜动脉缺血的临床特征和自然史
Cortney Connor1,2, Haley S D'Souza3, Raymond Iezzi3
1Department of Ophthalmology & Vision Science, University of California, Davis, Sacramento, California.
Ophthalmology science
|June 26, 2025
概括
分支视网膜动脉缺血 (BRAI) 涉及导致部分动脉阻塞的斑块,导致视网膜出血. 大多数BRAI患者长期保持良好的视力,尽管有血管风险因素.
科学领域:
- 眼科医生 眼科 眼科
- 血管医学 血管医学
- 视网膜成像 视网膜成像
背景情况:
- 分支视网膜动脉缺血 (BRAI) 是一种罕见的疾病,其特征是视网膜动脉由非动脉硬化斑块的慢性部分阻塞.
- 这种阻塞可以导致部门视网膜缺血和出血,影响视力.
研究的目的:
- 描述分支视网膜动脉缺血 (BRAI) 的临床特征和自然史.
- 确定与BRAI相关的关键诊断标准和患者特征.
主要方法:
- 一项回顾性多中心队列研究,涉及13名在2013年至2023年期间被诊断患有BRAI的患者.
- 诊断是基于视网膜动脉斑块的存在,部门出血,以及在光素血管学 (FA) 上延迟动脉流动.
- 长度数据,包括视敏度 (VA) 和成像 (色底,FA,OCT,OCT血管学) 被审查.
主要成果:
- 该研究包括13名患者,平均随访时间为1.7年. 平均年龄为74.2岁,男性为61.5%.
- 大多数患者都有显著的血管风险因素,包括高血压,高脂血症,动脉疾病和2型糖尿病.
- 超过50%的人保持良好的视力敏度 (≥20/25),在随访期间没有观察到斑点或新血管化的病例. 视网膜出血有所不同,但与VA或视网膜厚度无关.
结论:
- 分支视网膜动脉缺血是由视网膜动脉斑块,部门出血和延迟动脉流动的三位一体诊断的.
- 尽管有常见的全身血管风险因素,但BRAI患者通常保持良好的视力,并不会随着时间的推移出现重大并发症.
相关概念视频
01:27Atherosclerosis II: Clinical Manifestations and Diagnostic Tests
42
Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
42
01:21Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
39
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
39
01:30Peripheral Artery Disease I: Introduction
36
Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
36
01:17Ischemic Heart Disease: Overview
1.4K
Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
1.4K
01:21Aneurysm II: Clinical Manifestations and Diagnostic Studies
27
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
27
01:15Aortic Regurgitation I: Introduction
46
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
46