开发和验证胃食道逆流性疾病风险预测模型:胃食道逆流性疾病风险评分系统
Shanmathi Subramanian1, Umashri Sundararaju1, Hamrish Kumar Rajakumar2
1Department of General Surgery, Government Medical College, Omandurar Government Estate, Chennai 600002, Tamil Nādu, India.
World journal of gastrointestinal pathophysiology
|June 26, 2025
概括
一个新的GERD风险评分系统 (GRSS) 准确地识别了患胃食道逆流病 (GERD) 高风险的个体. 该工具有助于早期干预和GERD的初级预防策略.
科学领域:
- 胃肠病学 胃肠病学
- 公共卫生 公共卫生
- 预防医学 预防医学
背景情况:
- 胃食道逆流性疾病 (GERD) 的全球流行率上升与生活方式变化有关.
- GERD对公共卫生造成重大负担,影响生活质量并导致并发症.
- 缺乏有效的风险预测模型用于GERD初级预防.
研究的目的:
- 开发和验证一个GERD风险评分系统 (GRSS).
- 识别GERD高风险个体.
- 促进针对GERD的初级预防策略.
主要方法:
- 开发并验证了45项关于生活方式和人口风险因素的问卷.
- 利用回归模型创建预测方程和评分尺度.
- 在355名参与者的验证队列中评估模型性能.
主要成果:
- 确定了GERD和关键生活方式因素之间的显著关联.
- GRSS表现出强大的区分能力,高灵敏度和特异性.
- 取得了卓越的预测准确性,内部一致性和测试-重新测试可靠性.
结论:
- GRSS提供了一个验证的工具,用于GERD风险预测.
- 结合了数字方程和临床评分尺度,用于实际应用.
- 支持向初级预防转变,以管理日益增长的GERD负担.
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