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在RiPP生物合成中,通过一种新型细胞P450酶进行化的分子基础

Katie Nolan1, Remigio Usai1, Bingnan Li1

  • 1Department of Chemistry, University of Georgia, Athens, Georgia 30602, United States.

ACS catalysis
|June 26, 2025
PubMed
概括

这项研究揭示了RufO,一种独特的细胞染色体P450酶,如何结合和化其基质,用于鲁福米辛生物合成. 关键的结构和运动见解解释了它在核糖体合成和翻译后修饰 (RiPPs) 中独特的化机制.

关键词:
芳香性化芳香化.晶体结构 晶体结构细胞染色体P450酶的发生.核糖体合成和翻译后修饰的 (RiPP)鲁福米辛的生物合成光谱学表征的表征.基质与蛋白质的相互作用

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