病例报告:需要记住的一种血栓:在一个全腔肺循环患者中,华法林不符合病例
Saadullah H Ahmed1, Andrew Constantine1, Margarita Brida1,2
1Adult Congenital Heart Centre and Centre for Pulmonary Hypertension, Royal Brompton Hospital, Guy's and St Thomas' NHS Foundation Trust, Sydney Street, London SW3 6NP, UK.
European heart journal. Case reports
|June 26, 2025
概括
患有全腔肺循环 (TCPC) 的患者面临高血栓栓塞的风险. 在TCPC患者中,不遵守抗凝剂导致大动脉根栓塞和冠状动脉栓塞,强调需要严格遵守药物治疗.
科学领域:
- 心脏病学 心脏病学
- 血管外科 血管外科
- 儿童心脏病学 儿童心脏病学
背景情况:
- 全腔肺循环 (TCPC) 损害了脉动性血液流动,导致内皮功能障碍和高凝血状态.
- 患有Fontan型血液循环的患者患有静脉和动脉血栓栓塞的风险较高.
- 大动脉根栓塞是患有低可塑性左心综合征和TCPC的患者的罕见并发症.
研究的目的:
- 在患有TCPC的患者中呈现出大动脉根血栓症和冠状动脉栓塞病例.
- 强调复杂先天性心脏病患者对抗凝血剂的坚持的重要性.
主要方法:
- 一个25岁的男性患有TCPC和不良抗凝固固的病例报告.
- 急性冠状动脉综合征的临床表现.
- 大动脉根栓塞和右冠状动脉血栓栓塞的诊断发现.
主要成果:
- 这位患者出现了急性冠状动脉综合征,原因是右冠状动脉血栓栓塞,起源于大动脉根栓塞.
- 血栓溶解被选为冠状动脉干预,以避免脱离大动脉根的血栓.
- 血栓溶解取得了成功,患者得到了出院.
结论:
- 严格的抗凝药和定期随访对于患有Fontan型循环和Norwood修复的患者至关重要.
- 药物不合规可能会产生严重后果,包括危及生命的血栓栓塞事件.
- 有效的患者教育和持续的监测对于预防高风险人群中血栓栓塞的发生至关重要.
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