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Updated: Sep 18, 2025

Comparing the Affinity of GTPase-binding Proteins using Competition Assays
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Comparing the Affinity of GTPase-binding Proteins using Competition Assays

Published on: October 8, 2015

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先进的MD模拟方法揭示了小GTPase信号传输中的SH3域函数的机制

Muslum Yildiz1

  • 1Department of Molecular Biology and Genetics, Gebze Technical University, Kocaeli, Turkey.

Proteins
|June 26, 2025
PubMed
概括

分子动力学模拟揭示了对SH3-DLC1蛋白质复合体稳定性的关键见解. 与癌症相关的突变会改变相互作用,而复杂破坏性突变会破坏蛋白质结构的稳定.

关键词:
在ABF-MD中.DLC1 DLC1 的意思是DLC1.在GTPase信号传递中.我们的RhoGAP是RhoGAP.癌症 癌症 癌症 癌症 癌症

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