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Updated: Sep 18, 2025

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
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新型端粒向双药二核酸原药用于抗癌疗法

Ilgen Mender1, Romina Girotti1, Sergei Gryaznov1

  • 1Department of Research and Development, MAIA Biotechnology, Inc., Chicago, IL 60606, United States.

Nucleic acids research
|June 26, 2025
PubMed
概括

针对端粒酶的新型二核酸原药在体内显示出显著的抗癌疗效. 含有6-thio-2'-deoxyguanosine的MAIA-2022-12和MAIA-2021-20化合物显示出强大的抗瘤活性和免疫反应,为临床研究铺平了道路.

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