在重症成年人中 Delirium 严重性轨迹使用重症监护 Delirium 查清单:基于人口的队列
Heidi Lindroth1,2, Kirsten M Fiest3,4, Chel Hee Lee4,5
1Department of Nursing, Division of Nursing Research, Mayo Clinic Nursing Research Division, Rochester, MN .
Critical care medicine
|June 26, 2025
概括
这项研究在重症成年人中确定了五种 Delirium 严重性轨迹. 妄想轨迹的成员身份并没有预测出院后30天的死亡率,但趋势需要进一步调查.
科学领域:
- 关键护理医学 关键护理医学
- 神经科学是一个神经科学.
- 老年病的医生 老年病的医生
背景情况:
- 狂妄症在重症成年人中很常见,并且可以遵循不同的过程.
- 之前的研究建议根据严重程度和持续时间将妄分为几种轨迹.
- 这些结果轨迹的可重现性和预测价值仍然不清楚.
研究的目的:
- 用密集护理 Delirium 查清单 (ICDSC) 和 Delirium 持续时间来定义 Delirium 严重程度的轨迹.
- 评估轨迹成员与临床特征和出院后30天死亡率的关联.
主要方法:
- 在加拿大阿尔伯塔省的14个医疗外科ICU进行了回顾性,基于人口的队列研究.
- 包括21,071名ICU停留时间>=24小时和痴呆症 (ICDSC分数>=4) 的成年患者.
- 基于小组的轨迹建模在7天的时间内确定了5个 Delirium 严重性轨迹.
主要成果:
- 确定了五种不同的妄想轨迹:轻微短暂,严重快速恢复,严重缓慢恢复,轻微加速和严重不恢复.
- 轨迹成员身份与30天出院后的死亡率没有显著关联.
- 观察到轨迹和死亡率之间的临床相关趋势.
结论:
- 这项研究验证了一种概念验证模型,用于重症成年人中五种痴呆症严重性轨迹.
- 在这个队列中, Delirium 轨迹的成员身份没有预测出院后30天的死亡率.
- 需要进一步的研究来探索与生物标志物和患者相关结果的关联.
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