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Updated: Sep 18, 2025

Long-term Continuous EEG Monitoring in Small Rodent Models of Human Disease Using the Epoch Wireless Transmitter System
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优化使用人口药物动力学模型在重症患者中使用费诺巴比特的剂量,这些患者具有耐火和超耐火状态的

Maximilian Stoschus1,2, Moritz L Schmidbauer1, Johannes Starp2

  • 1Department of Neurology, Ludwig Maximilian University (LMU) Hospital, LMU Munich, Munich, Germany.

Epilepsia
|June 26, 2025
PubMed
概括

目前以体重为基础的剂量对耐火状态 (RSE) 和超耐火状态 (SRSE) 无效. 这项研究揭示了高的药理动力学变异性,导致非最佳的巴比塔尔剂量和低的目标在重症患者的实现.

关键词:
个性化剂量 个性化剂量重症监护病房的重症监护病房是一个重症监护病房.基于模型的精确剂量定量.神经密集型护理是指神经密集型护理.非线性混合效应建模非线性混合效应建模治疗药物监测 治疗药物监测

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