硫化和甲在呼吸测试中与人类小肠道的硫化生产者和甲基生物相关
Maria Jesus Villanueva-Millan1, Gabriela Leite1, Ruchi Mathur1,2
1Medically Associated Science and Technology (MAST) Program, Cedars-Sinai, 770 N. San Vicente Blvd, Suite G271, West Hollywood, CA, 90069, USA.
Digestive diseases and sciences
|June 26, 2025
概括
甲和硫化的呼吸测试与小肠微生物相关. 十二指肠中的特定细菌和古生物有助于呼吸气体水平,将肠道健康与呼吸分析联系起来.
科学领域:
- 微生物学 微生物学
- 胃肠病学 胃肠病学
- 呼吸分析 呼吸分析
背景情况:
- 呼吸测试 (BT) 显示与便微生物种群的相关性.
- 呼吸甲 (CH4) 与甲生物感染和便秘有关.
- 呼吸硫化 (H2S) 与H2S生产者和腹有关.
研究的目的:
- 为了研究小肠微生物和呼吸气体之间的关系.
- 为了确定十二指肠微生物组成是否影响呼吸中的甲和硫化水平.
主要方法:
- 参与者接受了CH4和H2S的空腹呼吸测试.
- 在食管胃管腺镜检查过程中采集了十二指管吸液.
- 使用猎枪测序分析了微生物DNA.
主要成果:
- 根据呼吸中的H2S水平,十二指肠细菌样本有显著差异.
- 更高的呼吸H2S与增加的十二指肠H2S产生细菌相关,如Proteus mirabilis.
- 在患有肠道甲素过度生长 (IMO) 的受试者中,十二指甲骨骨骨形状有所不同.
- 更高的呼吸CH4与增加的十二指肠甲原体相关,包括Methanobrevibacter smithii.
- 国际海事组织 (IMO) 发现,与特定甲原体的同时出现的情况更为普遍.
- 呼吸CH4与IMO阳性受试者的便秘严重程度相关.
- 特定的细菌与IMO阴性受试者的便一致性相关.
结论:
- 十二指肠 H2S 生产细菌有助于呼吸的 H2S 水平.
- 十二指腸甲原體古老菌對呼吸中的CH4水平有所貢獻.
- 呼吸测试可以反映小肠微生物的组成和活性.
关键词:
甲在细菌感染中幸存下来.类神奇动物 (Proteus mirabilis) 是一种神奇动物.呼吸测试是一种呼吸测试.十二指肠 (Duodenum) 是指十二指肠的一个部分.硫化是一种硫化.甲 甲 是一种微生物组是一个微生物组.更多相关视频
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