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Updated: Sep 18, 2025

Retroviral Infection of Murine Embryonic Stem Cell Derived Embryoid Body Cells for Analysis of Hematopoietic Differentiation
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在小鼠中,E3泛基因结合酶Cul5调节了造血干细胞功能,用于稳定状态的造血

Siera A Tomishima1, Dale D Kim1, Nadia Porter2

  • 1Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

The Journal of clinical investigation
|June 26, 2025
PubMed
概括

库林5 (CUL5) 调节了造血干细胞 (HSC) 的命运. 在小鼠中,CUL5的丧失导致异常的血细胞产生,可以通过JAK1/2抑制来纠正,揭示CUL5.

关键词:
骨髓的分化 骨髓的分化血液学 血液学 血液学造血干细胞 造血干细胞 造血干细胞免疫学 免疫学 免疫学干细胞是一种干细胞.乌比奎丁-蛋白质体系统

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