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Updated: Sep 18, 2025

Transfer of Manipulated Tumor-associated Neutrophils into Tumor-Bearing Mice to Study their Angiogenic Potential In Vivo
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抑制UPF1甲基化通过减少无意中介的mRNA衰变来增强瘤免疫治疗的敏感性

Shengyu Zhu1, Yucong Bai1, Dongjing Zhang1

  • 1GI Cancer Research Institute, Tongji Hospital, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, China.

Cell reports
|June 26, 2025
PubMed
概括

抑制UPF1甲基化通过削弱无意义介导的mRNA衰变 (NMD) 来增强结直肠癌 (CRC) 免疫性和抗PD-1治疗反应. 这为CRC免疫疗法提供了新的治疗点.

关键词:
CP: 癌症 癌症 癌症CP: 免疫学 免疫学在UPF1中,它是UPF1.自自是自的过程.癌症免疫疗法免疫疗法甲基化处理 甲基化处理无意义介导的mRNA衰变是无意义介导的

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