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Updated: Jun 29, 2026

Orthotopic Transplantation of Breast Tumors as Preclinical Models for Breast Cancer
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整合遗传多态和临床数据,开发乳腺癌放射治疗中皮肤毒性的预测模型

Ester Aguado-Flor1, Victoria M Reyes2, Víctor Navarro3

  • 1Hereditary Cancer Genetics Group, Vall d'Hebron Institute of Oncology (VHIO), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain; University of Barcelona, Barcelona, Spain.

Breast (Edinburgh, Scotland)
|June 26, 2025
PubMed
概括

通过将临床数据与遗传标记结合起来,可以更好地预测乳腺癌患者的放射治疗皮肤毒性. 这种方法提高了急性和晚期毒性模型的准确性.

关键词:
乳腺癌是什么? 乳腺癌是什么?文献候选多态体的验证非编码RNA多形态.预测模型的预测模型.辐射疗法诱导的副作用

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Genetic polymorphisms in drug targets have emerged as critical determinants of interindividual variability in drug response and toxicity. Pharmacogenomic investigations increasingly focus on identifying these variations to personalize and optimize therapeutic interventions. A drug target may be a receptor, enzyme, or signaling protein involved in pharmacologic responses or disease-related pathways. While early pharmacogenetic studies focused primarily on drug metabolism, current research...