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Updated: Sep 18, 2025

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在RUNX1-MECOM型白血病细胞中,HDAC抑制剂抑制Tek和Angpt1的表达和增殖

Fumi Nakamura1, Yuka Nakamura1, Ko Sasaki1

  • 1Department of Hematology and Oncology, Dokkyo Medical University, Tochigi, Japan.

Leukemia research
|June 26, 2025
PubMed
概括

基因组脱乙酶抑制剂 (HDACi) 显示出治疗RUNX1-MECOM急性大核细胞白血病的前景,通过阻断涉及angiopoietin 1和Tek的自身分泌循环,从而抑制白血病细胞生长.

关键词:
在英语中,Angpt1是Angpt1.自克林循环是自克林的循环.这是一种HDAC抑制剂.这是一种RUNX1-MECOM型白血病.一个是TEKTEK,一个是TEK.

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