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Updated: Sep 18, 2025

Generation of a RIP1 Knockout U937 Cell Line Using the CRISPR-Cas9 System
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Generation of a RIP1 Knockout U937 Cell Line Using the CRISPR-Cas9 System

Published on: April 11, 2025

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RIPK1感知到S-adenosylmethionine稀缺,从而导致细胞死亡和炎症

Zezhao Chen1, Xiaosong Gu2, Hongbo Chen3

  • 1Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201210, China; University of Chinese Academy of Sciences, Beijing 101408, China.

Cell metabolism
|June 26, 2025
PubMed
概括

RIPK1通过其代谢物SAM感知氨酸水平,作为细胞死亡的制动剂. 这种营养感应途径的干扰会触发亡和炎症,影响代谢平衡.

关键词:
在PRMT5中,在RIPK1中使用.这是一种S-adenosylmethionine.这就是TNF信号传递.灭症 (apoptosis) 是一种死亡的过程.死亡领域是死亡领域.这是一种炎症炎症炎症炎症.甲氨酸的使用方法甲基化处理的方法一个碳代谢的一个碳代谢.

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