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Updated: Sep 18, 2025

Generating De Novo Antigen-specific Human T Cell Receptors by Retroviral Transduction of Centric Hemichain
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支持TRBV28的分子基础+ T细胞对MR1-抗原的受体识别

Wael Awad1, Nicholas A Gherardin2, Lisa Ciacchi1

  • 1Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.

The Journal of biological chemistry
|June 26, 2025
PubMed
概括

粘膜关联不变T细胞 (MAIT) 使用T细胞受体 (TCR) 识别微生物抗原. 这项研究揭示了不同TCR基因的使用,特别是TCR-β链,如何改变抗原与MR1结合,影响免疫反应.

关键词:
马伊特 (MAIT) 的意思是说.与MHC相关的分子 1 1在TCR中,可以使用TCR.抗原呈现的呈现方式.蛋白质结构 蛋白质结构

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