持续使用大麻和中年期的眼睛健康
Kirsten Cheyne1, Rachael L Niederer2, Antony Ambler1
1Dunedin Multidisciplinary Health and Development Research Unit, Department of Psychology, University of Otago, Dunedin, New Zealand.
American journal of preventive medicine
|June 26, 2025
概括
成年人长期使用大麻并没有对中年人的眼睛健康造成伤害. 然而,持续使用大麻与更厚的质细胞内状层有关,这表明潜在的神经保护.
科学领域:
- 眼科医生 眼科 眼科
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
背景情况:
- 随着大麻合法化,大麻的使用在全球范围内越来越多.
- 大麻对眼睛的急性影响已知,但长期影响仍然不清楚.
- 了解慢性大麻使用对眼睛健康的影响至关重要.
研究的目的:
- 调查成年期持续使用大麻与中年期眼部健康措施之间的关联.
- 确定长期使用大麻是否会影响视觉敏度和视网膜血管结构.
- 探索对视网膜质细胞层的潜在神经保护作用.
主要方法:
- 从杜尼丁研究队列中对1,037名参与者的纵向研究,自出生以来一直跟踪.
- 从18岁到45岁通过自我报告评估大麻使用情况.
- 45岁时收集的眼部健康数据,包括视力敏度,视网膜血管口径和质细胞内状层厚度.
主要成果:
- 较高的大麻使用与视力敏度较差和视网膜动脉/静脉较宽相关.
- 随着大麻使用的增加,观察到质细胞内部形层的较厚的下半球场.
- 在调整了烟草吸烟和社会经济地位后,与视觉敏度和视网膜血管的关联是无意义的,但质细胞内状层的发现仍然存在.
结论:
- 持续使用大麻在45岁时对眼睛整体健康没有显著的有害或有益影响.
- 大麻使用者体内较厚的下游质细胞内状层表明了潜在的神经保护性质.
- 需要进一步的纵向评估,以充分阐明长期眼部神经保护与持续使用大麻的关系.
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