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表面粗性和湿透性对临时假肢的微生物粘附性的影响,这些假肢是由添加,减和常规方法制成的
Zeynep Sahin1, Nazire Esra Ozer1, Abdulhamit Calı2
1Department of Prosthodontics, Faculty of Dentistry, Lokman Hekim University, Çankaya, Ankara, Turkey.
European journal of oral sciences
|June 26, 2025
概括
3D打印的临时假肢比传统假肢具有更高的微生物粘附性. 这表明3Dresins可能会增加感染风险,需要进一步研究材料特性和微生物殖民.
科学领域:
- 生物材料科学 生物材料科学
- 微生物学 微生物学
- 牙科材料 牙科材料
背景情况:
- 越来越多地使用3D打印的临时假肢,突出了了解微生物对这些设备的粘附的差距.
- 假肢上的微生物殖民可能导致与生物材料相关的感染.
研究的目的:
- 评估和比较传统和数字制造的临时假肢材料的表面特性和微生物粘附性.
- 为了研究表面特征 (粗度,接触角度) 和微生物粘附之间的关系.
主要方法:
- 四种材料进行了测试:聚乙烯甲基酸盐 (PEMA),双烯复合物 (BA),CAD/CAM研磨的聚甲基酸盐 (PMMA) 和3D打印的二功能甲基酸盐树脂 (3Dresin).
- 评估了表面粗度,接触角度和微生物粘附 (黄金葡萄球菌,突变性菌株菌,白菌) 的情况.
- 扫描电子显微镜 (SEM) 用于视觉分析.
主要成果:
- 双烯复合材料 (BA) 的表面粗度最高,而BA和PEMA的接触角度高于PMMA和3Dresin.
- 黄金葡萄球菌在所有测试材料中表现出最高的附着性.
- 令人惊的是,3Dresin尽管表面粗度较低,但其微生物粘附度最高;微生物数量与表面粗度或接触角度之间没有显著的相关性.
结论:
- 传统生产的材料 (PEMA,BA) 比数字制造的材料 (PMMA,3Dresin) 更具有疏水性.
- 3D打印的树脂 (3Dresin) 可能会带来更高的微生物殖民和随后感染的风险.
- 需要进一步的研究来缓解3D打印生物材料上的微生物粘附.
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