性对内在大脑网络的动态结构-功能合的影响
Xi Zhang1, Dandan Li1, Yuting Yuan1
1College of Computer Science and Technology (College of Data Science), Taiyuan University of Technology, No. 79, Yingze West Street, Taiyuan, 030024, Shanxi, China.
Brain imaging and behavior
|June 26, 2025
概括
这项研究揭示了动态大脑连接的性别差异. 女性在某些大脑状态中表现出更强的结构功能合,影响认知表现.
科学领域:
- 神经科学是一个神经科学.
- 大脑的连接性 大脑的连接性
- 大脑功能的性别差异
背景情况:
- 已知性别之间的静态结构-功能合 (SC-FC) 差异.
- 人类大脑神经活动的动态性质并不能被静态模型所捕捉.
- 了解性别对时间变化的SC-FC合的影响对于大脑组织洞察至关重要.
研究的目的:
- 为了研究动态功能连接 (FC) 强度和SC-FC合的性别差异.
- 在内在的功能网络层面分析这些差异.
- 探索动态SC-FC合和跨性别认知表现之间的关系.
主要方法:
- 使用滑动窗口方法构建动态FC网络.
- 采用k-means集群来识别超连接和低连接的大脑状态.
- 分析了使用两个窗口大小 (50 TR 和 30 TR) 的SC-FC合.
主要成果:
- 女性在超连接状态下表现出更高的全脑SC-FC合,特别是在默认模式的网络系统中.
- 雌性在低连接状态期间在边缘/边缘和皮层下网络中也表现出更高的FC强度和合.
- 在超连接状态下,男性在体感/运动和听觉网络中表现出更大的FC强度和合.
结论:
- 在不同大脑状态的动态SC-FC合中存在显著的性别特异性模式.
- 这些模式与认知表现相关,这表明认知功能的神经发育基础.
- 这项研究为有关性对大脑动态和认知的影响提供了新的见解.
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