一种具有抗菌活性的双杆菌菌株,其抗菌特性和体外益生菌研究
Jing Ji1,2,3, Tiange Li1, Baoying Ma1
1School of Environmental Science and Engineering, Tianjin University, Tianjin 300072, China.
Microorganisms
|June 27, 2025
概括
这种细菌是Bifidobacterium sp. 菌株TF04表现出强大的抗菌活性,对抗食物传播的病原体. 这种益生菌菌株在酸性条件下也表现出极好的生存能力和强大的肠道殖民潜力,使其成为食品保存的理想选择.
科学领域:
- 食品微生物学 食品微生物学
- 益生菌 益生菌 益生菌
- 抗微生物药物是一种抗菌剂.
背景情况:
- 在食品安全方面,对天然抗微生物药物的需求日益增加.
- 需要具有抗菌性能的有效益生菌菌株.
- 对Bifidobacterium sp. 的评价 菌株TF04用于食品保存应用.
研究的目的:
- 为了识别和表征一种强大的抗微生物益生菌菌株.
- 评估Bifidobacterium sp.的抗菌疗效和益生菌潜力. 这是TF04菌株TF04菌株.
- 评估TF04在食品应用中的稳定性和安全性.
主要方法:
- 对23种益生菌菌株的抗菌活性进行选.
- 对大肠杆菌,金黄色葡萄球菌和上皮葡萄球菌的抑制区直径的确定.
- 评估TF04在酸性和胆汁条件下的生存,自聚,疏水性,抗氧化能力和安全性 (血液溶解和凝酶活性).
主要成果:
- 这种细菌是Bifidobacterium sp. 菌株TF04显示出对大肠杆菌 (12.85毫米),黄金杆菌 (14.85毫米) 和上皮杆菌 (17.50毫米) 的显著抑制区.
- 主要的抗菌化合物是蛋白质,在pH 2-4时具有最佳活性,在热和紫外线暴露下稳定.
- 在pH值为2.0的情况下,TF04的活力高 (>45%),在3%的胆盐中生存率高于55%,强烈的自聚 (40.10%),疏水性 (>30%) 和抗氧化能力. 没有观察到血液溶解或凝酶活性.
结论:
- 这种细菌是Bifidobacterium sp. 菌株TF04是一种有前途的多功能益生菌,具有强大的抗菌活性和优良的益生菌特性.
- TF04的稳定性,安全性和肠道殖民潜力使其成为天然食品保存的强有力的候选人.
- 需要进一步的研究来净化生物活性化合物,并在食品系统中验证TF04.
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