超声波作为预测不确定的甲状腺结节恶性病的作用 - 一个多中心研究
Reem J Al Argan1, Dania M Alkhafaji1, Feras M Almajid2
1Department of Internal Medicine, College of Medicine, Imam Abdulrahman Bin Faisal University, King Fahad Hospital of the University, Dammam 31441, Eastern Province, Saudi Arabia.
Medicina (Kaunas, Lithuania)
|June 27, 2025
概括
超声波的特征,如低声组合,微化和淋巴结参与,有助于预测未确定甲状腺结节中的恶性瘤. 这些发现有助于在甲状腺癌风险分层的手术决策.
科学领域:
- 内分泌学 在内分泌学.
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
背景情况:
- 不确定的甲状腺结节 (贝塞斯达III和IV) 由于它们具有中间恶性瘤风险,因此存在诊断挑战.
- 准确的风险分层对于指导临床决策和避免不必要的手术至关重要.
研究的目的:
- 评估超声波在不确定性甲状腺结节的风险分层和恶性病预测中的作用.
- 支持临床决策,减少甲状腺结节不必要的手术干预.
主要方法:
- 对18岁以上接受过甲状腺手术的患者进行了回顾性多中心队列研究.
- 包括在2016年至2022年间具有不确定的细胞学 (贝塞斯达III或IV) 的结节.
- 收集有关人口统计,甲状腺功能,超声波特征,细胞学和组织病理学的数据.
主要成果:
- 在223个不确定的结节中,总体恶性瘤发病率为46.6%.
- 恶性瘤的独立预测因素包括固体低声组合,微化,淋巴结参与,ATA和TI-RADS类别4-5.
- 与ATA和TI-RADS分类相比,微化和淋巴结参与等个体特征显示出更高的特异性和正预测值 (PPV).
结论:
- 超声波特征和分类系统 (ATA,TI-RADS) 是不确定的甲状腺结节中恶性瘤的重要预测因素.
- 个别超声波特征为恶性瘤检测提供了更高的特异性和PPV.
- 超声波风险分层对于指导手术决策有价值,建议对低风险结节进行进一步评估.
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