对婴儿的食习惯和口腔免疫的比较分析
Amal Mohamad Husein Mackawy1, Fay Saleh Alturky1, Amal Hussain Mohammed1
1Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah 51452, Saudi Arabia.
Medicina (Kaunas, Lithuania)
|June 27, 2025
概括
母乳养支持健康的婴儿口腔微生物群和上皮健康,而配方养与炎症增加和细菌生长有关. 这项研究强调了母乳养对婴儿口腔健康的保护性益处.
科学领域:
- 口腔微生物学 口腔微生物学
- 婴儿免疫学 婴儿免疫学
- 儿科卫生健康 儿科卫生健康
背景情况:
- 婴儿养实践显著影响口腔微生物群的发展和免疫反应.
- 哺乳促进有益细菌和口腔健康,而配方养可能会增加致病细菌和炎症风险.
- 了解这些影响对于婴儿口腔健康管理至关重要.
研究的目的:
- 研究母乳养与配方养对口腔细菌生长的影响.
- 评估对婴儿口腔上皮细胞完整性和17-interleukin (IL-17) 表达的影响.
- 为了比较1-12个月龄的母乳养和配方养婴儿之间的口腔健康标志物.
主要方法:
- 从卡西姆地区招募了60名婴儿 (30名母乳养,30名配方养).
- 使用殖民地形成单位 (CFU) 量化口腔细菌,并通过显微镜评估上皮形态.
- 使用酶相关免疫吸收试验 (ELISA) 测量了口服IL-17度,并进行了统计分析.
主要成果:
- 配方奶粉养的婴儿的IL-17水平明显较高,表明炎症增加 (p < 0.001).
- 与配方奶粉养的婴儿相比,母乳养的婴儿表现出改善的上皮健康,降低炎症和减少碎片.
- 在配方奶粉养的婴儿中观察到较高的细菌负载,与表皮质完整性受损相关.
结论:
- 配方食与IL-17升高,细菌殖民增加和上皮质完整性受损有关,这表明一种促炎状态.
- 母乳养显示出保护作用,促进口腔微生物组的平衡和强大的上皮健康.
- 这些发现强调了母乳养对婴儿口腔健康的免疫和微生物优势.
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