达沙替尼和奎尔塞丁组合在急性叶酸诱导的实验性病症中增加了损伤

Antonio Battaglia-Vieni1,2, Vanessa Marchant1,2, Lucia Tejedor-Santamaria1,2

  • 1Molecular and Cellular Biology in Renal and Vascular Pathology Laboratory, Department of Medicine, IIS-Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Avda. Reyes Católicos, 2, 28040 Madrid, Spain.

概括

达沙替尼加奎尔塞丁 (D&Q) 的老化药物组合在小鼠中没有防止急性损伤 (AKI). D&Q治疗加剧了一些有害反应,这表明在AKI中对临床翻译要谨慎.

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