用于非侵入性皮肤癌生物传感器的SiN数字里埃变换光谱仪的数值分析
Miguel Ángel Nava Blanco1, Gerardo Antonio Castañón Ávila1
1School of Engineering and Science, Tecnologico de Monterrey, Ave. Eugenio Garza Sada 2501, Monterrey 64849, Mexico.
Sensors (Basel, Switzerland)
|June 27, 2025
概括
这项研究介绍了一种新的化拉曼光谱系统,用于非侵入性皮肤癌检测. 这项技术对准确,实时的诊断充满希望,可能减少对活检的需求.
科学领域:
- 生物医学光学 生物医学光学
- 材料科学 材料科学 材料科学
- 医学诊断 医学诊断 医学诊断
背景情况:
- 传统的黑色素瘤诊断依赖于视觉评估和活检,面临精度限制和观察者之间的变化.
- 像拉曼光谱这样的非侵入性诊断技术为早期皮肤癌检测提供了潜在的潜力.
- 为了便携式使用,缩小拉曼光谱仪是具有挑战性的,因为信号弱和光干扰.
研究的目的:
- 在化平台上对一个集成的数字里埃变换光谱仪进行数值分析,用于拉曼光谱.
- 开发一种便携式实时系统,用于非侵入性皮肤癌诊断.
- 重建和分析拉曼光谱,以区分良性和恶性皮肤病变.
主要方法:
- 在化平台上的基于开关的数字里埃变换光谱仪的数值分析.
- 将光谱仪与单个光功率计相合以进行检测.
- 使用规范回归方法进行拉曼光谱重建 (800-1800厘米-1).
主要成果:
- 从良性和恶性皮肤病变中成功重建了拉曼光谱.
- 证明了该系统能够区分各种皮肤癌类型的能力.
- 验证了化平台的可行性,用于集成紧型拉曼光谱仪.
结论:
- 拟议的化数字里叶变换光谱仪是一种可行的皮肤癌非侵入性诊断传感器.
- 这项技术可以提高诊断精度,并可能减少对活检的依赖.
- 光子学的进步使医疗应用的紧和高效的光谱装置成为可能.
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