在患有慢性肌肌痛的患者中出现中心敏感,焦虑和抑郁症状
Piotr Seweryn1, Marta Waliszewska-Prosol2, Adriana Petrasova3
1Department of Experimental Dentistry, Wroclaw Medical University, Wroclaw, Poland.
Journal of oral rehabilitation
|June 27, 2025
概括
中枢敏感性 (CS) 与慢性肌疼痛 (CMMP) 中的焦虑和抑郁有显著的相关性. 解决这些心理因素和CS对于改善CMMP患者的治疗结果至关重要.
科学领域:
- 疼痛医学 医学 疼痛医学
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
背景情况:
- 慢性口肌痛 (CMMP) 是一个常见的关节障碍 (TMD) 症状.
- 中枢敏感性 (CS) 和焦虑和抑郁等心理因素是已知的导致慢性疼痛的因素.
- 在CMMP中,CS与焦虑和抑郁症的具体相互作用尚未得到充分理解.
研究的目的:
- 研究CMMP患者中CS,焦虑和抑郁症状之间的关系.
- 评估CMMP患者中这些因素之间的相关性.
主要方法:
- 206名CMMP患者完成了临床检查 (DC/TMD) 和验证的问卷 (CSI,PHQ-9,GAD-7).
- 使用GCPS和NRS测量疼痛的严重程度.
- 统计分析发现了相关性和群体差异.
主要成果:
- 在CS (CSI) 和焦虑 (GAD-7) 和抑郁 (PHQ-9) 评分之间观察到显著的正相关性.
- 较高的CS得分与增加的肌肌肉疼痛强度有关.
- 与男性相比,女性报告CS,焦虑和抑郁的得分较高.
结论:
- 中央敏感化,心理困扰 (焦虑,抑郁) 和慢性肌肌痛之间存在显著联系.
- 对CMMP的管理应包括解决心理因素和中枢神经系统敏感化的策略.
- 这些综合方法可能会改善CMMP患者的治疗结果.
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