一级性过症:一个更新的审查
Mahan Maazi1, Alexander Kc Leung2, Joseph M Lam3
1Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Drugs in context
|June 27, 2025
概括
原发性过症 (PHH) 影响全球多达9%的人,其特点是过度出汗. 管理涉及各种治疗,但长期疗效和副作用需要进一步研究.
科学领域:
- 皮肤病学 皮肤病学
- 临床医学 临床医学
- 医学研究 医学研究
背景情况:
- 过 (HH) 是超出温度调节需求的过度出汗.
- 它被分类为一次性 (异质性) 过 (PHH) 或二次性过 (SHH).
- 本综述侧重于PHH流行病学,病因发生,诊断和管理.
研究的目的:
- 提供一次性过症 (PHH) 的最新概述.
- 突出目前PHH的药理和程序治疗选择.
- 讨论PHH对患者生活质量的影响.
主要方法:
- 在2025年2月进行了全面的文献搜索.
- 搜索的数据库包括Ovid Medline,EMBASE和Cochrane CENTRAL. 这些数据库的搜索数据库包括Ovid Medline,EMBASE和Cochrane CENTRAL.
- 包括的研究是在过去10年内发表的,涵盖了各种类型的研究.
主要成果:
- 全球PHH患病率在0.072%至9%之间,占HH病例的93%.
- PHH与交感过度活动有关;SHH具有多种潜在原因.
- 管理包括局部,全身,基于设备,注射和手术的选择,具有不同的疗效和副作用.
结论:
- 原发性过严重影响患者的生活质量,造成身体和社会心理上的痛苦.
- 个性化,多模式的治疗方法对于最佳管理至关重要.
- 需要进一步的研究来改进现有疗法,并探索新的治疗方式.
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