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Updated: Sep 17, 2025

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
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Published on: October 4, 2019

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在Saccharomyces cerevisiae中有效生产7-脱水胆固醇的途径重构

Yuchen Han1,2, Huayi Gao3, Shuo Wang3

  • 1Key Laboratory of Engineering Biology for Low-carbon Manufacturing, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China.

ACS synthetic biology
|June 27, 2025
PubMed
概括

这项研究将酵母改造为产生7-脱胆固醇 (7-DHC),这是维生素D的前体. 优化策略导致7-DHC产量大幅增加,在生物反应堆中达到3.26g L-1以实现可持续生产.

关键词:
7-脱胆固醇的使用方法这种植物是Saccharomyces cerevisiae.生物合成生物合成细胞工厂 细胞工厂膜结构结构的膜结构.过氧体向的向性向

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