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在阿拉伯成年人中探索代谢肥胖现象和动脉样硬化心血管疾病风险

Kaiser Wani^1,2, Balvir Kumar², Nasser M Al-Daghri¹

¹Chair for Biomarkers of Chronic Diseases, Biochemistry Department, College of Science, King Saud University, Riyadh, Saudi Arabia.

Clinical obesity

|June 27, 2025

概括

代谢健康的肥胖 (MHO) 增加了动脉样硬化心血管疾病 (ASCVD) 的风险,特别是当BMI定义时. 视觉脂肪指数 (VAI) 比BMI更好地识别有风险的个体,无论性别如何.

科学领域:

心脏病学和新陈代谢健康
公共卫生和流行病学

背景情况:

肥胖是全球日益严重的公共卫生问题.
代谢健康状况显著影响心血管疾病风险.
传统的肥胖指标可能无法完全捕捉相关的健康风险.

研究的目的:

调查沙特成年人中各种代谢性肥胖表型中的10年动脉样硬化心血管疾病 (ASCVD) 风险.
为了比较体质指数 (BMI) 和内脏肥胖指数 (VAI) 在识别代谢健康肥胖 (MHO) 和高ASCVD风险的个体中的有效性.

主要方法:

一组5460名沙特成年人 (40-79岁) 根据代谢状态,BMI和VAI进行了分类.
使用ASCVD风险估计器+计算了10年ASCVD风险得分.
使用统计分析,包括赔率比率,来比较不同类型的风险.

主要成果:

与代谢健康正常体重 (MHNW) 个体相比,代谢健康肥胖 (MHO) 个体的ASCVD风险得分明显更高.
当通过BMI定义肥胖时,男性的MHO显示出更大的ASCVD风险的几率比率要高得多.
当肥胖的特征是VAI时,具有高VAI (MHHV) 的代谢健康个体的ASCVD风险与正常VAI的个体相似,独立于性别,这表明VAI是一个优越的指标.

结论:

代谢健康的肥胖 (MHO) 与沙特成年人10年ASCVD风险增加有关.
视觉肥胖指数 (VAI) 是比BMI更有效的工具来识别具有高ASCVD风险的代谢健康个体.
这些发现强调了在心血管风险评估中考虑内脏脂肪的重要性.

关键词:

这是一个ASCVD.动脉样硬化心血管疾病身体质量指数 (BMI) 是指身体质量指数.评估心血管风险评估代谢综合征代谢综合征内脏脂肪度指数是什么

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