一种肠道MALT淋巴瘤病例,其特征是扩散的毛细血管增生结节与出血
Ming Zhong1, Wei Wei1, Tingyu Wang1
1Gastroenterology, Zigong First People's Hospital.
Revista espanola de enfermedades digestivas
|June 27, 2025
概括
这项研究报告了一例与粘膜相关的淋巴组织 (EMZL) 外节边缘区域淋巴瘤的病例,呈现为复发性血. 通过结肠镜检查,活检和免疫组织化学染色来确认诊断,揭示了这种惰性淋巴瘤的特征发现.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 粘膜关联淋巴组织的外节边缘区域淋巴瘤 (EMZL) 是一种惰性非霍奇金淋巴瘤.
- 胃肠道干扰是EMZL的常见表现,通常模仿炎症性肠道疾病.
研究的目的:
- 提出一个EMZL病例诊断在一个52岁的男性呈现出血.
- 要突出EMZL在结直肠和末端大肠中的诊断特征.
主要方法:
- 用窄带成像 (NBI) 进行结肠镜检查,以可视化粘膜变化.
- 结节性病变的深度活检在结直肠和末端大肠.
- 活检样本的组织病理学检查和免疫组织化学染色 (CD20,CD79a,BCL-2,Ki67,CD43).
主要成果:
- 结肠镜检查显示了扩散的"小石"外观,带有结节性粘膜突出和超塑性毛细血管.
- NBI显示了毛细血管的"根状"分支.
- 组织病理学证实中度至重度的慢性粘膜炎症,淋巴细胞增生以及对EMZL阳性的免疫组织化学标志物.
结论:
- 这些发现表明,作为诊断,粘膜相关的淋巴组织 (惰性) 的额外边缘区域淋巴瘤.
- 在患有复发性血和特征性内镜发现的患者的差异诊断中应考虑EMZL.
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