衰老会影响由TLR2/TLR4激活的树突细胞诱导的CD4+T细胞两极化和粘膜热流

Sara Zúquete1,2, Mariana Ferreira1,2, Inês L S Delgado1,2,3

  • 1CIISA-Centro de Investigação Interdisciplinar em Sanidade Animal, Faculdade de Medicina Veterinária, Universidade de Lisboa, Avenida da Universidade Técnica, Lisboa 1300-477, Portugal.

PubMed
概括

在老化的树突细胞 (DCs) 中,收费类受体 (TLR) 的激活会损害T细胞的归向,并改变细胞因子配置. 了解这些与年龄相关的DC功能变化对于开发有效的免疫调节策略至关重要.

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