相关实验视频

Updated: Sep 17, 2025

A Simple and Inexpensive Running Wheel Model for Progressive Resistance Training in Mice
06:59

A Simple and Inexpensive Running Wheel Model for Progressive Resistance Training in Mice

Published on: April 28, 2022

3.8K

通过AMPK/PGC1α信号传递,GW8510可以缓解小鼠的肌肉缩和骨肌肉功能障碍

Yutong Chen1, Zurui Liu2, Chen Liu2

  • 1Peking University International Cancer Institute, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, P.R. China.

International journal of molecular medicine
|June 27, 2025
PubMed
概括

GW8510是一种CDK2抑制剂,通过增强肌肉质量,力量和线粒体功能,有效地对抗肌肉缩. 它激活AMPK/PGC1α通路,为与年龄有关的肌肉损失提供了潜在的治疗策略.

关键词:
这就是AMPKK.在GW8510中,GW8510是什么?这就是Pgc1α.变质化 (denervation) 是指一个变质化的过程.德克萨米他是一种肌肉缩 肌肉缩 肌肉缩

更多相关视频

Author Spotlight: Exploring Orofacial Muscle Regeneration – Insights and Innovations06:33

Author Spotlight: Exploring Orofacial Muscle Regeneration – Insights and Innovations

Published on: December 29, 2023

1.0K
Isolation and Differentiation of Primary Myoblasts from Mouse Skeletal Muscle Explants06:53

Isolation and Differentiation of Primary Myoblasts from Mouse Skeletal Muscle Explants

Published on: October 15, 2019

17.6K

相关概念视频

PI3K/mTOR/AKT Signaling Pathway01:22

PI3K/mTOR/AKT Signaling Pathway

The mammalian target of rapamycin  (mTOR) is a serine/threonine kinase that regulates growth, proliferation, and cell survival in response to hormones, growth factors, or nutrient availability. This kinase exists in two structurally and functionally distinct forms: mTOR complex 1  (mTORC1) and mTOR complex 2  (mTORC2). The first form (mTORC1) is composed of a rapamycin-sensitive Raptor and proline-rich Akt substrate, PRAS40. In contrast,  mTORC2 consists of a...
4.0K