发展障碍的青少年和年轻成年人使用激素药物的月经管理:系统性审查和元分析
Dehlia Moussaoui1, Judith Laqua1, Victoria L Crofts2
1Division of General Pediatrics, Department of Pediatrics, Obstetrics and Gynecology, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Geneva, Switzerland.
概括
激素药物有效地管理发展障碍 (DD) 的青少年的月经障碍,改善症状和满意度. 副作用是最小的,支持这个人群平等获得月经保健.
科学领域:
- 生殖健康 生殖健康
- 青少年医学 青少年医学
- 关于残疾人的研究.
背景情况:
- 发展障碍 (DD) 的青少年经历的月经障碍与同龄人相似,具有独特的挑战.
- 有激素药物可供使用,但它们对DD青少年的影响还未得到充分研究.
- 了解这一群体的月经管理对于适当的护理至关重要.
研究的目的:
- 评估荷尔蒙药物对DD的青少年和年轻成年人月经管理的疗效.
- 评估患者的满意度,副作用和与这些治疗相关的并发症.
- 为DD的青少年提供有关月经健康的临床实践信息.
主要方法:
- 对Medline,Embase,Cochrane图书馆和PsycNet数据库进行系统审查.
- 关键词包括月经管理,激素药物,青少年和残疾.
- 对各项研究的综合结果进行了比例的元分析.
主要成果:
- 包括20项涉及3317名参与者的研究.
- 月经管理减少了出血和增加了缺血率 (LNG-IUD用户的45.4%).
- 报告高满意度,突破性出血是最常见的副作用;没有发生静脉血栓栓塞.
结论:
- 月经管理显著改善了DD的青少年的月经症状和满意度.
- 在这个群体中,激素治疗显示副作用和并发症的发生率很低.
- 研究结果支持DD的青少年平等获得月经保健.
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