心灵胜过物质:血液透析患者的认知衰退:一个横截面分析
Vidya Sagar Ram1, Anita Anita1, Aaditya Shivhare2
1Department of Medicine, Uttar Pradesh University of Medical Sciences, Etawah, Uttar Pradesh, India.
Annals of African medicine
|June 27, 2025
概括
患有慢性病 (CKD) 接受血液透析 (HD) 的患者与保守管理相比,表现出显著的执行功能缺陷. 常规认知查对于改善CKD患者护理至关重要.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
背景情况:
- 慢性病 (CKD) 影响全球健康,影响高达15%的人口.
- 认知障碍在CKD患者中很常见,特别是那些接受血液透析 (HD) 的人.
研究的目的:
- 为了在印度保守管理的CKD患者和HD患者之间的认知表现进行比较.
- 为了确定受血液透析影响的特定认知领域.
主要方法:
- 一项对1214名末期CKD患者 (604名保守,610名高强度) 的观察性,横截面研究.
- 神经认知评估包括MMSE,ACE-III,格罗伯和巴斯克测试,Trail Making测试,Stroop测试和波士顿命名测试.
- 统计分析使用了威尔科克森和奇平方测试.
主要成果:
- 血液透析患者的ACE-III视空间分数较低 (P=0.00685) 和语言抑制控制受损 (P=0.011).
- 在全球认知 (MMSE) 或其他ACE-III领域中没有发现显著差异.
- 16.7%的HD患者Stroop测试得分不足;33.3%由于视力问题无法完成.
结论:
- 血液透析与前额执行功能的选择性缺陷有关.
- 研究结果表明,皮下和血管病理生理学可能是这些缺陷的基础.
- 常规认知查推用于CKD患者,以指导治疗和改善结果.
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