将有色人种纳入统一议定书的随机对照试验:系统性审查
Lorraine T Benuto1,2, Stephanie R Reyes3, Valeria Ramirez4
1DICE Center, Reno, 505 South Arlington Suite 102 Reno, NV, 89509, USA. dr.benuto@gmail.com.
Journal of racial and ethnic health disparities
|June 27, 2025
概括
在统一议定书的临床试验中,少数民族和种族的代表性不足,这限制了对其在不同人群中的有效性的理解. 提供了建议,以改善未来的研究包容性和减少健康差异.
科学领域:
- 临床心理学 临床心理学
- 医疗保健服务研究 医疗服务研究
- 基于证据的实践.
背景情况:
- 临床研究,特别是随机对照试验 (RCT),往往缺乏多样性,主要包括非拉丁裔白人参与者.
- 这限制了基于证据的治疗结果在不同种族和种族群体的概括性.
- 跨诊断治疗的有效性,如统一议定书,在少数群体中仍然在很大程度上是未知的,因为代表性不足.
研究的目的:
- 系统地审查有关统一议定书 (UP) 的现有文献.
- 评估UP的RCT中少数民族和种族少数群体的包容率.
- 确定提高临床结果研究中代表性不足的群体代表性的关键建议.
主要方法:
- 使用PsycInfo,EMBASE,PubMed和Medline进行了已发表的RCT的系统审查.
- 研究的重点是统一议定书,包括少数民族或种族少数群体.
- 提取的数据包括人口统计,招聘策略,诊断,治疗参数和结果.
主要成果:
- 审查包括从457.7的初始搜索中的19篇文章.
- 在评估统一议定书的RCT中,发现少数民族和种族少数群体的代表人数不足.
- 数据总结了青少年和成人人口的人口统计,招聘,诊断,治疗和结果.
结论:
- 在统一议定书的RCT中发现,少数民族和种族群体的代表性显著不足.
- 极其需要改善多元人群在临床研究中的参与.
- 建议建议指导临床科学家进行更具包容性的研究和减轻健康不平等.
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