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在多发性骨髓瘤初始检查中异常的单独外膜扩散性脏参与使用2-[ 18 F]FDG-PET/CT成像

Bastien Jamet¹, Cyrille Touzeau², Chloe Antier²

¹Nantes Université, Univ Angers, CHU Nantes, INSERM, CNRS, CRCI2NA, Médecine Nucléaire, Nantes, France.

Clinical nuclear medicine

|June 27, 2025

概括

2-[18F]FDG-PET/CT扫描可以揭示多发性骨髓瘤 (MM) 罕见的脏参与. 这种病例在PET/CT上表现出扩散性脏外脊髓性疾病 (EMD),与典型的MM呈现不同.

科学领域:

在瘤学瘤学.
核医学是一种核医学.
放射学放射学是一门学科.

背景情况:

多发性骨髓瘤 (MM) 常见地表现为骨髓参与.
在MM中,外脊髓性疾病 (EMD) 往往在疾病的晚期被检测出来.
2-[18F]FDG-PET/CT是分期和检测MM EMD的一个有价值的工具.

研究的目的:

在新诊断的MM中报告一种异常的单独扩散脏EMD病例.
为了说明2-[18F]FDG-PET/CT在识别非典型的MM EMD模式中的实用性.
突出MM中扩散器官参与的潜力.

主要方法:

一名63岁的新诊断MM的妇女接受了2-[18F]FDG-PET/CT.
图像检测显示,体积显著增加,双侧皮层吸收强烈,扩散.
脏活检证实了外骨髓质瘤的参与.

主要成果:

2-[18F]FDG-PET/CT扫描确定了扩散脏EMD作为外骨髓性疾病的唯一部位.
脏干扰呈现为增加脏大小和强烈的皮质FDG吸收.
尿排泄腔没有可视化,这表明功能受损或透.

结论:

这种病例表明MM的不常见呈现与扩散性脏EMD.
2-[18F]FDG-PET/CT可以检测异常模式的外骨髓瘤,包括扩散器官透.
这些发现强调了在MM诊断和分期时考虑扩散器官参与的重要性.

关键词:

这是一种外骨髓性疾病.脏受影响脏受影响多发性骨髓瘤是多发性骨髓瘤的一种疾病.

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