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部分中间轮切除与对嗅觉功能的保护:系统性审查和元分析

Yen-An Chen¹, Chih-Hao Chen^1,2,3,4, Wei-Hsin Wang^2,5

¹Department of Otolaryngology-Head and Neck Surgery, Taipei Veterans General Hospital, Taipei, Taiwan.

Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale

|June 27, 2025

概括

与中间轮保护 (MTP) 相比,部分中间轮切除 (MTR) 不会对嗅觉功能产生负面影响. 客观测试有利于MTR,表明它可能是临床环境中首选的选择.

科学领域:

耳鼻喉科耳鼻喉科耳鼻喉科
鼻科鼻科是指鼻科的专家.
嗅觉神经科学是一种神经科学.

背景情况:

中间轮 (MT) 在嗅觉功能中发挥作用,但其手术管理仍有争议.
在鼻腔手术期间,部分切除与MT的保存是嗅觉结果的关键考虑因素.

研究的目的:

为了比较部分中轮切除 (MTR) 和中轮保存 (MTP) 之间的嗅觉结果.

主要方法:

在主要数据库 (Cochrane Library,Embase,PubMed,Scopus,Web of Science) 进行了系统的文献搜索,截至2024年2月10日.
包括七项符合条件的研究,比较部分MTR和MTP之间的嗅觉结果.
使用随机效应模型计算嗅觉功能得分的标准化平均差异 (SMD),并进行子组分析.

主要成果:

总的来说,在部分MTR和MTP之间没有发现嗅觉的显著差异 (SMD,0.140;P = .359).
小组分析显示,在客观嗅觉测试中,部分MTR具有显著的益处 (SMD,0.370;P < .001).
在主观测试,功能性内镜外科手术,骨底部手术的内镜内腔方法或超过6个月的随访持续时间中没有发现显著差异.

结论:

与中间轮保护 (MTP) 相比,部分中间轮切除 (MTR) 不会导致嗅觉功能障碍.
鉴于客观测试中观察到的潜在益处,部分MTR可能是临床实践中有利的外科手术方法.

关键词:

通过内镜进行内的方法.功能性内镜鼻外科手术中间轮机维护保护中间轮机切割切除嗅觉功能是一种嗅觉功能.

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