相关实验视频

Updated: Sep 17, 2025

Murine Ileocolic Bowel Resection with Primary Anastomosis

Murine Ileocolic Bowel Resection with Primary Anastomosis

Published on: October 29, 2014

完全或部分内镜治疗对克罗恩病的长期结果的影响:一个前性的多中心研究

Clara Yzet¹, Franck Brazier¹, Elise Derval¹

¹Gastroenterology department, Amiens University Hospital, Amiens, France.

Journal of Crohn's & colitis

|June 27, 2025

概括

在克罗恩氏病 (CD) 患者中实现完整的内镜治疗 (EH) 可以减少长期并发症. 与完全的EH相比,部分EH与治疗失败和住院的风险更高.

科学领域:

胃肠病学胃肠病学
炎症性肠道疾病研究研究
临床内镜检查临床内镜检查

背景情况:

根据STRIDE II指南,内镜治疗 (EH) 是克罗恩病 (CD) 的关键治疗目标.
完整的EH可能在减少长期CD并发症方面提供进一步的好处.

研究的目的:

评估内镜愈合程度与CD患者长期并发症风险之间的关联.
为了比较实现完全EH与部分EH的患者之间的结果.

主要方法:

一项前性多中心研究,涉及128名CD患者,在2019-2022年期间对EH进行评估.
完全EH (CDEIS=0) 和部分EH (CDEIS>0但<4) 的患者之间的治疗失败率的比较.
主要终点:治疗失败,包括药物强化,皮质类固醇使用,住院,肠切除,狭窄/状腺发育或近部疾病.

主要成果:

平均22个月的随访后,31%的患者经历了治疗失败.
部分EH与治疗失败的风险显著增加相关 (43%对25%,P=.036).
患有部分EH的患者患有CD相关住院的风险显著增加 (17%对2.5%,P=.005).

结论:

完整的内镜治疗似乎与CD患者的更有利的长期结果有关,与部分EH相比.
需要进一步的高功率研究来证实这些发现,并巩固完整的EH的作用.
实现完全的EH可能是改善克罗恩病的长期管理的关键目标.

关键词:

克罗恩氏病是什么克罗恩氏病是什么粘膜的治愈粘膜的治疗

更多相关视频

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Published on: May 26, 2023

Robotic D3 Partial Duodenal Resection with Primary Side-to-Side Anastomosis

Robotic D3 Partial Duodenal Resection with Primary Side-to-Side Anastomosis

Published on: December 15, 2023

相关概念视频

Inflammatory Bowel Disease V: Surgical Management

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...