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超分子 π-π 相互作用实现高负荷,并从功能化石墨烯氧化物纳米载体中提供依赖pH的拉帕提尼布的受控释放

Samiksha Dewangan1, Nidhi Singh1, Omkar Kailas Gaikwad1

  • 1Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research, Kolkata 700054, WB, India.

Molecular pharmaceutics
|June 27, 2025
PubMed
概括

功能化石墨烯氧化物 (GO) 通过π-π相互作用增强了拉帕提尼布 (LPT) 的负载,改善了转移性乳腺癌治疗的药物输送. 这种新的系统提供了受控释放和增加的细胞毒性,解决了药物动力学限制.

关键词:
功能化的功能化.石墨烯氧化物 石墨烯氧化物拉帕提尼布 (lapatinib) 是一种治疗方法.释放特征的释放特征是什么π-π 堆叠的堆叠方式

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