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Updated: Sep 17, 2025

Tracking Bispecific Antibody-Induced T Cell Trafficking Using Luciferase-Transduced Human T Cells
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基于BAFF的三功能T细胞参与剂触发了针对B细胞恶性瘤的强大的瘤免疫力

Shuhong Li1, Licai Shi1, Qiaoru Guo1

  • 1State Key Laboratory of Chemical Oncogenomics, Shenzhen Key Laboratory of Chemical Genomics, Peking University Shenzhen Graduate School, Shenzhen 518055, China.

Protein & cell
|June 27, 2025
PubMed
概括

使用BAFF配体的新型T细胞参与剂 (TCE) 在B细胞恶性瘤中显示出前景. 最优的TriBAFF/CD3/ABDCon构造有效准瘤和T细胞,优于现有疗法.

关键词:
在B细胞恶性瘤中.这种T细胞的参与者是T细胞.抗体工程是针对抗体的工程.免疫系统的逃脱是免疫逃脱.多种特异性的抗体.自然连接剂天然的连接剂.

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