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Updated: Sep 17, 2025

Mass Spectrometry and Luminogenic-based Approaches to Characterize Phase I Metabolic Competency of In Vitro Cell Cultures
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Mass Spectrometry and Luminogenic-based Approaches to Characterize Phase I Metabolic Competency of In Vitro Cell Cultures

Published on: March 28, 2017

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来自和人类的CYP4B1酶的功能分析揭示了催化功能适应的进化热点

Saskia Hüsken1, Annika Röder2, Johannes Ptok3

  • 1Department of Otorhinolaryngology, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine-University, Düsseldorf, Germany.

PLoS genetics
|June 27, 2025
PubMed
概括

人类CYP4B1酶在灵长类动物进化的早期,在猿类和子分裂之前,失去了活性. 猿类和人类的遗传变化使这种关键酶失活,影响了灵长类动物的进化.

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