积极的外部腰部排水在儿科异常性内高血压的使用和提出一种新的治疗算法
Bahattin Tanrikulu1, Muruvvet Ayten Tuzunalp, Ugur Isik
1Acibadem University School of Medicine, Department of Neurosurgery, Division of Pediatric Neurosurgery, Istanbul, Türkiye.
Turkish neurosurgery
|June 27, 2025
概括
外部腰部排水 (ELD) 结合口服药物有效降低了儿科异常性内高血压 (IIH) 的内压力 (ICP) 和视网膜神经纤维层厚度. 这种主动的方法提供了一种安全和快速的方法来管理IIH症状.
科学领域:
- 儿科神经学 儿科神经学
- 眼科医生 眼科 眼科
- 神经外科 神经外科
背景情况:
- 儿童的异常性内高血压 (IIH) 可以导致明显的视力损伤.
- 内压升高 (ICP) 是IIH的一个标志,常常导致皮囊胀.
- 标准治疗包括口服药物,但快速减少ICP至关重要.
研究的目的:
- 评估外部腰部排水 (ELD) 作为儿科IIH口服药物的辅助药物的疗效.
- 为了确定是否同时使用ELD和口服药物加快ICP下降和 papilledema解决.
- 评估与ELD相关的安全性和并发症在这个人群中.
主要方法:
- 用ELD和口服药物治疗IIH的儿科患者的回顾性研究.
- 在ELD前后的测量包括眼科检查,视觉连贯性断层扫描 (OCT) 视网膜神经纤维层 (RNFL) 厚度,以及通过腰部穿刺进行ICP.
- 平均年龄为10.9岁;平均ELD持续时间为8.7天.
主要成果:
- 平均ICP从ELD前的447毫米H2O显著下降到ELD后的263.1毫米H2O.
- 在ELD后,RNFL厚度也在两只眼睛显著减少.
- 在随访期间,四名患者需要进行腰关节分流手术;没有报告重大并发症.
结论:
- 积极的外部腰部排水是儿科IIH的有效辅助疗法.
- ELD促进了ICP和RNFL厚度的快速减少.
- 这种方法在治疗儿科IIH时似乎是安全和有益的.
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