瘤整形手术与乳腺切除:并发症和生存结果
Gabriel De la Cruz Ku1, Anshumi Desai2, Carly Wareham3
1Department of Surgery, University of Massachusetts Medical School, Worcester, Massachusetts; Universidad Cientifica del Sur, Lima, Peru.
The Journal of surgical research
|June 27, 2025
概括
瘤塑性手术 (OPS) 显示出较少的并发症和更好的乳腺癌存活率,而不是乳腺切除术 (MT). 与MT-RT相比,OPS+RT为早期乳腺癌患者提供了更好的结果.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 乳腺癌研究研究 乳腺癌研究
背景情况:
- 在乳腺癌治疗中比较瘤整形手术 (OPS) 和乳腺切除术 (MT).
- 评估风险因素和术后并发症的发生频率.
- 评估对乳腺癌特定存活率 (BCSS) 的影响.
研究的目的:
- 为了比较OPS和MT之间的术后并发症.
- 为了确定OPS和MT之间的BCSS差异.
- 在乳腺癌患者中确定BCSS的预后因素.
主要方法:
- 来自国家外科质量改善计划和SEER癌症档案的患者的分析.
- 包括接受OPS与放射治疗 (OPS+RT) 和没有放射治疗的乳腺切除术 (MT-RT) 的女性乳腺癌患者.
- 对并发症率和生存结果的统计比较.
主要成果:
- 乳房切除术 (MT) 与整体,手术和伤口并发症的风险更高有关 (ORs从1.673到2.501,P<0.001).
- 与放射治疗 (OPS+RT) 进行的瘤塑性手术显示,与MT-RT (93.8%,P < 0.001) 相比,5年BCSS (98.1%) 优越.
- MT-RT被确定为BCSS的负预后因素 (HR = 2.140,P = 0.009).
结论:
- 与MT相比,OPS与整体,手术和伤口并发症的比率较低.
- 与MT相比,OPS在早期乳腺癌患者中显示出改善的BCSS.
- OPS+RT提供了比MT-RT更好的生存结果.
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