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在怀孕期间的饮食模式和接触非持久性内分泌干扰化学物质

Sarah Warkentin¹, Sandra Márquez¹, Hana Vespalcová¹

¹ISGlobal, Barcelona, Spain; Spanish Consortium for Research on Epidemiology and Public Health (CIBERESP), Madrid, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain.

Environment international

|June 27, 2025

概括

孕妇遵循植物性饮食可能会减少对某些内分泌干扰化学物质 (EDC) 的暴露. 相反,西方和动物蛋白质饮食增加了对EDCs的暴露,如酸盐,PAHs和农药.

科学领域:

环境健康环境健康
营养流行病学营养流行病学
生殖健康生殖健康

背景情况:

怀孕期间暴露于非持久性内分泌干扰化学物质 (EDC) 是普遍存在的,并与不良健康结果有关.
饮食是EDC暴露的重要来源,需要确定与更高暴露水平相关的饮食模式.
了解饮食和EDC暴露之间的关系对于公共卫生干预至关重要.

研究的目的:

调查怀孕期间饮食模式与接触非持久性EDC之间的关联.
确定可能增加或减少孕妇EDC暴露的特定饮食习惯.
为孕妇提供饮食建议,以尽量减少EDC暴露.

主要方法:

分析了来自巴塞罗那生命研究队列 (BiSC) 的640名孕妇队列.
使用食物频率调查问卷评估了饮食模式,包括超加工食品 (UPF) 消费和遵守地中海饮食.
测量了各种EDC代谢物的尿液含量,包括酸盐,DINCH,pyrifos,pyrethroids,PAHs,有机酸盐,和 parabens.

主要成果:

对"素食"或地中海饮食的更高坚持与一些酸盐代谢物的较低水平有关.
"西方"和"动物蛋白"的饮食模式,以及UPF摄入量,与PAH,农药和酸盐代谢物的水平增加有关.
虽然观察到关联,但在对多次比较进行调整后,没有一个仍然具有统计学意义.

结论:

基于植物的饮食模式可能有助于在怀孕期间减少暴露于特定的酸盐和有机酸盐代谢产物.
富含动物产品,脂肪,糖和盐的饮食可能会增加对PAH,农药和酸盐的暴露.
饮食选择是影响孕妇暴露EDC的可改变因素.

关键词:

群组研究是指群组研究.饮食饮食饮食饮食饮食模式饮食模式内分泌干扰物干扰内分泌干扰物甲酸的含量甲酸的含量怀孕怀孕怀孕怀孕

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